1.01894

Brij^® 35 solution

(30% w/w in water) for biochemistry

• Synonym(s): Polyoxyethylene (23) Lauryl Ether, Polyoxyethylene lauryl ether, Polyoxyethyleneglycol Dodecyl Ether
• UNSPSC Code: 12352401

Properties

• Quality Level: 100
• form: liquid
• pH: 5-7 (20 °C in H₂O)
• density: 1.03 g/cm³ at 20 °C
• storage temp.: 15-25°C

Description

General description

Brij^® 35 is a common nonionic surfactant, which has a dodecyl apolar core and a polyoxyethylene chain-formed polar surface. It comprises several hydrophobic and hydrogen-bonding interaction sites with target analytes. Brij 35 is edible and non-toxic.

Application

Brij^® 35 solution has been used to develop a novel hexafluoroisopropanol (HFIP)/Brij-35 supramolecular solvent (SUPRAS)-based liquid-phase microextraction (LPME) of parabens. It has also been used to study the formation of water-in-ionic liquid (w/IL) microemulsions in IL 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim][PF6]).

Biochem/physiol Actions

Brij^® 35 is known as the “green” modifier in micellar liquid chromatography due to its capability to simulate the biopartitioning process. It forms water-in-ionic liquid (w/IL) microemulsions with IL 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim][PF6]) in the bulk phase. It can also form reverse micelle-type aggregates inside [bmim][PF6] in the absence of added water.

Analysis Note

Identity (IR-spectrum): conforms
Turbidity: ≤ 2.0 NTU
(equivalent to turbidityclass I according to DAB)

Legal Information

Brij is a registered trademark of Croda International PLC

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315 - H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable