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MilliporeSigma
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Key Documents

07-415

Sigma-Aldrich

Anti-Sam 68 Antibody

serum, Upstate®

Synonym(s):

Anti-Sam68, Anti-p68

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human, rat

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_006559

UniProt accession no.

Q07666

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... KHDRBS1(10657)

Specificity

Sam 68

Immunogen

Peptide corresponding to residues 331-348 of human Sam 68

Application

Anti-Sam 68 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of Sam 68 & has been validated in IP, WB, ICC.
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

Quality

routinely evaluated by immunoblot in RIPA lysates from HeLa cells

Target description

68kDa

Physical form

0.1M Trisglycine,pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Antiserum

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Naomi Li et al.
Nucleic acids research, 44(18), 8726-8741 (2016-07-02)
Sam68 is a known sequence-specific RNA binding protein that regulates alternative splicing events during the cell cycle and apoptosis. Sam68 has also been shown to influence transcription, but the molecular mechanism remains undefined. Herein we identify Sam68 as a transcriptional
T Chen et al.
Molecular biology of the cell, 10(9), 3015-3033 (1999-09-03)
The GSG (GRP33, Sam68, GLD-1) domain is a protein module found in an expanding family of RNA-binding proteins. The numerous missense mutations identified genetically in the GSG domain support its physiological role. Although the exact function of the GSG domain
Zhenzhong Deng et al.
Neoplasia (New York, N.Y.), 16(8), 656-664 (2014-09-16)
p53 is one of the most important tumor suppressor genes involved in human carcinogenesis. Although downstream targets of p53 and their biologic functions in cancer cells have been extensively investigated, it is still far from the full understanding. Here, we

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