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Anti-phospho-FGFR-1 (Tyr653/Tyr654) Antibody

from rabbit, purified by affinity chromatography

Basic fibroblast growth factor receptor 1, FGFR-1, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, Proto-oncogene c-Fgr, CD331

biological source


Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies



purified by

affinity chromatography

species reactivity


species reactivity (predicted by homology)

bovine (based on 100% sequence homology), mouse (based on 100% sequence homology), rat (based on 100% sequence homology), zebrafish (based on 100% sequence homology), chicken (based on 100% sequence homology), Xenopus (based on 100% sequence homology)


antibody small pack of 25 μg


cell based assay: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in


Gene Information

human ... FGFR1(2260)

General description

FGFR-1 (fibroblast growth factor receptor 1) is a member of the basic fibroblast growth factor family of proteins and is thought to be important in the induction and propagation of benign prostatic hyperplasia. A shortage of FGFR-1 causes death post-implantation and has been linked to neurofascin and neurite outgrowth. FGFR-1 expression has recently been found to be increased in patients with renal cell carcinoma and FGFR-1 may also have a role to play in early limb formation.


This antibody recognizes FGFR-1 phosphorylated at Tyr653/Tyr654.


Epitope: Phosphorylated Tyr653/Tyr654
KLH-conjugated linear peptide corresponding to human FGFR-1 phosphorylated at Tyr653/Tyr654.


Detect phospho-FGFR-1 (Tyr653/Tyr654) using this Anti-phospho-FGFR-1 (Tyr653/Tyr654) Antibody validated for use in WB, Cell Function Assay.
Peptide Inhibition Assay Analysis: 0.2 µg/mL from a representative lot peptide blocked in HEK293T cells transfected with FGFR-1.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors


Evaluated by Western Blot in untreated and lambda phosphatase-treated HEK293T cells transfected with FGFR1.

Western Blot Analysis: 0.2 µg/mL of this antibody detected FGFR-1 in 10 µg of untreated and lambda phosphatase-treated HEK293T cells transfected with FGFR1.

Target description

~145 kDa observed.
FGFR-1 has 19 isoforms and eight potential glycosylation sites that increase the expected size to 120 kDa for the immature form and 145 kDa for the mature form of the receptor (Hisaoka, K., et al. (2011). JBC. 286(24):21118-21128).

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Untreated and lambda phosphatase-treated HEK293T cells transfected with FGFR-1

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Certificate of Analysis

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Certificate of Quality

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