Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

05-23-3831

Sigma-Aldrich

BQ-123, Sodium Salt

A highly potent, selective, and competitive ETA (endothelin) receptor antagonist (Ki = 40 nM for ETA versus Ki = 2.5 µM for ETB).

Synonym(s):

BQ-123, Sodium Salt

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C31H41N6O7 · Na
Molecular Weight:
632.68
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

A highly potent and selective ETA (endothelin) receptor antagonist (Ki = 40 nM for ETA versus 2.5 µM for ETB).
A highly potent, selective, and competitive ETA (endothelin) receptor antagonist (Ki = 40 nM for ETA versus Ki = 2.5 μM for ETB).

Biochem/physiol Actions

Cell permeable: no
Primary Target
ETA (endothelin) receptor antagonist
Product does not compete with ATP.
Reversible: no
Target Ki: 40 nM for ETA versus 2.5 µM for ETB

Packaging

Yes

Warning

Toxicity: Standard Handling (A)

Sequence

Cyclo(D-Asp-Pro-D-Val-Leu-D-Trp, Na)

Physical form

Supplied as a sodium salt. Sold on the basis of peptide content.

Other Notes

Nambi, P., et al. 1996. J. Pharmacol. Exp. Ther.277, 1567.
Bax, W.A., and Saxena, P.R. 1994. Trends Pharmacol. Sci. 15, 379.
Ihara, M., et al. 1991. Biochem. Biophys. Res. Commun. 178, 132.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service