03-0146-00

SMC^® Amyloid Beta 42 High Sensitivity Kit

1 kit sufficient for 96 wells, input: serum, plasma, cerebrospinal fluid (CSF)

• Synonym(s): Abeta 1-42 immunoassay kit, Abeta 42 Single Molecule Counting Kit, Abeta 42 immunoassay kit, Abeta 42 ultra-sensitive Immunoassay
• UNSPSC Code: 12161503
• NACRES: NA.84

Properties

• Quality Level: 200
• usage: kit sufficient for 96 wells
• species reactivity: human, rat, mouse
• manufacturer/tradename: SMC^®
• assay range: sensitivity: 0.98 pg/mL; (lower limit of quantification); inter-assay cv: <20%; intra-assay cv: <15%; standard curve range: 0.24-250 pg/mL
• technique(s): ELISA: suitable; single molecule counting: suitable
• input: serum; plasma; cerebrospinal fluid (CSF)
• compatibility: for use with SMCxPRO^® and Erenna<TMSYMBOL></TMSYMBOL> (validated)
• shipped in: wet ice
• storage temp.: 2-8°C

Description

General description

The SMC^® Amyloid β1-42 High Sensitivity Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format.

Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2)The Erenna and SMCxPRO^® immunoassay systems detect analytes using Single Molecule Counting (SMC^®) technology.

Specificity

The capture antibody recognizes the C-terminal end of Amyloid beta 1-42, conferring specificity for Aβ42. No significant cross-reactivity to Aβ38 and Aβ40 was observed.

Legal Information

SMC is a registered trademark of Singulex

SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302 + H332,H311,H319,H360FD,H373,H412
• pcodes: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation
• target_organs: Respiratory Tract
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects