N-007
Naltrexone solution
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
About This Item
Recommended Products
grade
certified reference material
Quality Level
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
forensics and toxicology
format
single component solution
shipped in
wet ice
storage temp.
2-8°C
SMILES string
Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)CC6CC6
InChI
1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1
InChI key
DQCKKXVULJGBQN-XFWGSAIBSA-N
Gene Information
human ... OPRD1(4985) , OPRK1(4986) , OPRM1(4988)
General description
Application
- Naltrexone research solution: Research utilizes naltrexone in thermosensitive gels to enhance microneedle-assisted transdermal delivery, showcasing its potential for non-invasive therapeutic applications and improving drug bioavailability (Polymers (Basel), 2021; doi: 10.3390/polym13060933).
- Opioid receptor antagonist: A study discusses the historical context of opioid use disorder trials, with naltrexone featured as a pivotal medication in optimizing treatment strategies. This research underscores its importance in addiction studies and the development of effective treatment modalities (Addict Sci Clin Pract, 2021; doi: 10.1186/s13722-021-00223-z).
- Naltrexone in vitro study: The compound is utilized in a model of ocular neuropathic pain, highlighting its utility in pain management research and its potential role in developing new therapeutic strategies for chronic pain conditions (Transl Vis Sci Technol, 2019; doi: 10.1167/tvst.8.2.6).
- Naltrexone pharmacological research: Research on Mg²⁺ influx modulation in cardiac myocytes provides insights into ionic exchanges in heart tissues, demonstrating naltrexone′s broader applications in physiological and pharmacological studies (J Physiol Sci, 2019; doi: 10.1007/s12576-018-0625-5).
- Naltrexone biochemistry application: A study explores mechanical stimulation for reducing ethanol self-administration in rats, indicating naltrexone′s utility in experimental models of addiction and its potential application in behavioral sciences (Evid Based Complement Alternat Med, 2017; doi: 10.1155/2017/6578621).
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Legal Information
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
Storage Class
3 - Flammable liquids
wgk_germany
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
Certificates of Analysis (COA)
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Articles
Although both biphenyl and phenyl-hexyl phases can resolve these compounds, the former exhibits excellent peak shape and substantially less silanol-derived ion exchange activity.
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