B-030

Butalbital-D₅ solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonym(s): Butalbital-D₅ solution
• Empirical Formula (Hill Notation): C₁₁D₅H₁₁N₂O₃
• CAS Number: 145243-96-5
• Molecular Weight: 229.29
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• InChI: 1S/C12H18N2O3/c1-4-6-12(7-5-8(2)3)9(15)13-11(17)14-10(12)16/h4,8H,1,5-7H2,2-3H3,(H2,13,14,15,16,17)/i1D2,4D,6D2
• InChI key: OFGPEYHYGSLQGU-LDEUCTAFSA-N

Description

General description

A certified analytical reference solution and internal standard applicable for use in butalbital testing methods by GC/MS or LC/MS for applications in clinical toxicology, urine drug testing or forensic analysis. Butalbital is a barbiturate often combined with other medications such as acetaminophen or aspirin for the treatment of pain or codeine for headaches. Trade names of several butalbital combinations include Axocet^®, Bucet, and Bupap^® with acetaminophen and Axotal with aspirin.

Application

• Butalbital-D₅ in analytical research:Utilizing stable isotope-labeled compounds like Butalbital-D₅ enhances the precision of mass spectrometry analyses for monitoring drug metabolism and identifying potential drug interactions, providing reliable data critical for patient safety and effective treatment protocols. (Guo et al., 2024).


• Detection in complex matrices:The butalbital-D₅ is used to improve the detection of trace compounds in complex biological matrices in clinical toxicology studies, helping to accurately assess drug therapeutic levels and potential toxicities. (Yi et al., 2024).

Legal Information

Axocet is a registered trademark of Fougera Pharmaceuticals Inc.

Bupap is a registered trademark of ECR Pharmaceuticals Co., Inc.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes,Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup