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880127C

Avanti

DSPE-PEG(2000) PDP

Avanti Research - A Croda Brand 880127C

Synonym(s):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[PDP(polyethylene glycol)-2000] (ammonium salt)

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About This Item

CAS Number:
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (880127C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 880127C

concentration

10 mg/mL (880127C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C\NC(CCSSC1=CC=CC=N1)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.

General description

DSPE-PEG(2000) PDP is a functionalized polyethylene glycol (PEG) conjugated lipid.

Application

DSPE-PEG(2000) PDP has been used in the preparation of targeted liposomes. It has also been used as a PEGylated lipid for antibody conjugation to vesicles.

Biochem/physiol Actions

DSPE-PEG(2000) PDP serves as a precursor of DSPE-PEG2000-SH.

Packaging

5 mL Clear Glass Sealed Ampule (880127C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The use of pH-triggered leaky heterogeneities on rigid lipid bilayers to improve intracellular trafficking and therapeutic potential of targeted liposomal immunochemotherapy
Karve S, et al.
Biomaterials, 30(30), 6055-6064 (2009)
Antitumor efficacy following the intracellular and interstitial release of liposomal doxorubicin
Bandekar A, et al.
Biomaterials, 33(17), 4345-4352 (2012)
Multifunctional nanoliposomes with curcumin--lipid derivative and brain targeting functionality with potential applications for Alzheimer disease
Mourtas S, et al.
European Journal of Medicinal Chemistry, 80, 175-183 (2014)

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