860663P
Avanti
Sphingosine (d22:1)
Avanti Research™ - A Croda Brand 860663P, powder
Synonym(s):
D-erythro-Sphingosine (C22 base)
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About This Item
Empirical Formula (Hill Notation):
C22H45NO2
CAS Number:
Molecular Weight:
355.60
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
form
powder
packaging
pkg of 1 × 1 mg (860663P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860663P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCCCCCC
General description
Sphingosine (d22:1) is a sphingosine with 20 carbon long chain bases (LCB). It is a component of Asterias amurensis glucosylceramide.
Biochem/physiol Actions
Sphingosine negatively regulates cell proliferation and induces apoptosis. It has an ability to regulate the activities of phospholipases, protein kinases, ion channels, cannabinoid receptor type 1 (CB-1) receptors and steroidogenic factor 1 (SF-1) receptors.
Packaging
5 mL Amber Glass Screw Cap Vial (860663P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Certificates of Analysis (COA)
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Daisuke Mikami et al.
Journal of oleo science, 65(8), 671-680 (2016-07-20)
Asterias amurensis starfish provide several bioactive species in addition to being fishery waste. Glucosyl ceramides (GlcCers) were extracted from the viscera of these starfish and were isolated by silica gel column chromatography. Degraded GlcCers generated A. amurensis sphingoid bases (ASBs)
Olivier Cuvillier
Biochimica et biophysica acta, 1585(2-3), 153-162 (2003-01-18)
The sphingolipid metabolites ceramide, sphingosine, and sphingosine 1-phosphate contribute to controlling cell proliferation and apoptosis. Ceramide and its catabolite sphingosine act as negative regulators of cell proliferation and promote apoptosis. Conversely, sphingosine 1-phosphate, formed by phosphorylation of sphingosine by a
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