850371P

22:0 PC

1,2-dibehenoyl-sn-glycero-3-phosphocholine, powder

• Synonym(s): 1,2-didocosanoyl-sn-glycero-3-phosphocholine; PC(22:0/22:0)
• Empirical Formula (Hill Notation): C₅₂H₁₀₄NO₈P
• CAS Number: 37070-48-7
• Molecular Weight: 902.36
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 g (850371P-1g); pkg of 1 × 25 mg (850371P-25mg); pkg of 1 × 500 mg (850371P-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850371P
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C52H104NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-51(54)58-48-50(49-60-62(56,57)59-47-46-53(3,4)5)61-52(55)45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h50H,6-49H2,1-5H3
• InChI key: HRTBOPUWPUXROO-UHFFFAOYSA-N

Description

General description

Phosphatidylcholines (PCs) are amphipathic molecules, that are mainly located on the outer leaflets of the biological membrane bilayer. Approximately 40–50% of the total cellular phospholipids consists of phosphatidylcholine.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

22:0 PC may be used:

• to study its effects on non-amyloidogenic processing of amyloid precursor protein (APP)/α-secretase activity
• to prepare a lipid monolayer to study whether ligand is specifically targeted to domains containing Cu(II)-iminodiacetate lipid (Cu-PSIDA)
• as a lipid standard for the quantification of lipid species from lipid droplets by hydrophilic interaction liquid chromatography-high performance liquid chromatography (HILIC-HPLC)

Biochem/physiol Actions

Phosphatidylcholines (PCs) can serve as lung surfactant.

Packaging

20 mL Clear Glass Screw Cap Vial (850371P-1g)

20 mL Clear Glass Screw Cap Vial (850371P-500mg)

5 mL Amber Glass Screw Cap Vial (850371P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable