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850315C

Avanti

08:0 PC

1,2-dioctanoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

PC(8:0/8:0)

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About This Item

Empirical Formula (Hill Notation):
C24H48NO8P
CAS Number:
19191-91-4
Molecular Weight:
509.61
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850315C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850315C

concentration

10 mg/mL (850315C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine (PC), a major phospholipid is mostly found in the membrane of mammals. The headgroup of this bilayer-forming lipid carries a positively and negatively charged quaternary amine and a phosphate respectively. 08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine) is a saturated synthetic short-chain phospholipid.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

08:0 PC (1,2-dioctanoyl-sn-glycero-3-phosphocholine) has been used to form a lipid film to study its effect on P-glycoprotein′s (P-gp′s) activity/to compare its effect with TWEEN®80 and Cremophor®EL. It may be used to study its effect on the nicotinamide adenine dinucleotide (NADH): n-decylubiquinone (DBQ) activity of complex I. It may also be used as a bicellar model to study their phase behavior.

Packaging

5 mL Clear Glass Sealed Ampule (850315C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
Cremophor is a registered trademark of BASF SE
TWEEN is a registered trademark of Croda International PLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk_germany

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 null
Phase behavior of a binary lipid system containing long- and short-chain phosphatidylcholines
Sun HY, et al.
Royal Society of Chemistry Advances, 7(10), 5715-5724 null
Teruhiko Baba et al.
Chemistry and physics of lipids, 227, 104870-104870 (2020-01-10)
Interfacial properties and membrane protein solubilization activity of a series of partially fluorinated octyl-phosphocholine (PC) surfactants were investigated from the viewpoint of the fluorination degree of the hydrophobic chain. The critical micelle concentration (CMC), surface tension lowering activity, molecular occupied

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