840512C

16:0 Phosphatidylethanol

1,2-dipalmitoyl-sn-glycero-3-phosphoethanol (sodium salt), chloroform

• Synonym(s): 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanol (sodium salt)
• Empirical Formula (Hill Notation): C₃₇H₇₂O₈PNa
• CAS Number: 92609-90-0
• Molecular Weight: 698.93
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (840512C-25mg); pkg of 1 × 20 mL (840512C-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 840512C
• concentration: 10 mg/mL (840512C-25mg); 25 mg/mL (840512C-500mg)
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCC)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C37H73O8P.Na/c1-4-7-9-11-13-15-17-19-21-23-25-27-29-31-36(38)42-33-35(34-44-46(40,41)43-6-3)45-37(39)32-30-28-26-24-22-20-18-16-14-12-10-8-5-2;/h35H,4-34H2,1-3H3,(H,40,41);/q;+1/p-1/t35-;/m1./s1
• InChI key: MAGNEPCJIVJZIK-RUQJKXHKSA-M

Description

General description

Phosphatidylethanol (PEth) is an abnormal phospholipid found in the cellular membrane. It is spotted in the liver, skeletal muscle, brain and kidney of rat when its mainly exposed to ethanol. 16:0 Phosphatidylethanol/(1,2-dipalmitoyl-sn-glycero-3-phosphoethanol) has two palmitic acid chains.

Application

16:0 Phosphatidylethanol (Peth)/(1,2-dipalmitoyl-sn-glycero-3-phosphoethanol) may be used:

• as an internal standard in liquid chromatography−mass spectrometry (LC-MS) analysis of PEth in human whole blood
• as an internal standard to spike blood samples for in liquid chromatography high-resolution mass spectrometry (LC−HRMS) analysis
• as a standard in calibration curve generation and validation of ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-ESI-MS/MS)

Biochem/physiol Actions

Phosphatidylethanol can be used as a biomarker in blood for chronic alcohol use.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (840512C-500mg)

5 mL Clear Glass Sealed Ampule (840512C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• target_organs: Liver,Kidney, Respiratory system
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash