640009
Avanti
siRNA Delivery Kit
Avanti Research™ - A Croda Brand 640009, powder
Synonym(s):
siRNA Delivery Kit, Delivery System for siRNA/DNA
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About This Item
UNSPSC Code:
12161503
NACRES:
NA.25
Recommended Products
form
powder
manufacturer/tradename
Avanti Research™ - A Croda Brand 640009
packaging
1 ea of 1 × (with stopper and crimp cap)
shipped in
dry ice
storage temp.
−20°C
General description
The self-assembly of custom-synthesized MVL5 and GMO with siRNA results in the formation of a double-gyroid bicontinuous inverted cubic phase with colocalized lipid/siRNA domains. The high charge density (due to MVL5) and positive Gaussian modulus of the GMO-containing membranes confer optimal electrostatic and elastic properties for endosomal escape, enabling efficient siRNA delivery and effective, specific gene silencing.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (640009-1EA)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Certificates of Analysis (COA)
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Cecília Leal et al.
Langmuir : the ACS journal of surfaces and colloids, 27(12), 7691-7697 (2011-05-27)
The self-assembly of a custom-synthesized pentavalent cationic lipid (MVL5) and glycerol monooleate (GMO) with small interfering RNA (siRNA) results in the formation of a double-gyroid bicontinuous inverted cubic phase with colocalized lipid/siRNA domains as shown by synchrotron X-ray scattering and
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