330651
Avanti
GM1 ELISA (Clear)
Avanti Polar Lipids
Synonym(s):
GM1 ELISA, GM1 ELISA Snoopers®, Clear, for use in absorbance applications
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
41116158
NACRES:
NA.84
form
liquid
manufacturer/tradename
Avanti Polar Lipids
packaging
1 ea of 1 × (ELISA strip packaged in foil pouch)
shipped in
wet ice
storage temp.
2-8°C
General description
Avanti Lipid Snoopers® are lipid microarrays with lipid spotted on solid support and are useful in semi-quantitative measurements. These snoopers are relatively stable and provide high sensitivity compared to the conventional enzyme-linked immunosorbent assay (ELISA) methods. Ganglioside GM1 (monosialotetrahexosylganglioside) is present in the brain and comprises one sialic acid moiety and unsaturated acyl chains. GM1 is catabolized by the enzyme GM1 β-galactosidase.
ELISA Snoopers® are 8-well strips pre-coated with a single high-quality lipid species. They can be used to investigate protein-lipid interactions, and characterize and titrate lipid binding proteins. This format provides the following advantages:
The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.
- quantitative lipid-protein binding studies
- assemble a 96-well plate using only the lipids of interest for binding studies
- flexibility - use 8 to 96 wells, and 1 to 12 lipids as needed.
The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.
Biochem/physiol Actions
Avanti Lipid Snoopers® aid in probing protein–lipid interaction by chemiluminescent detection method. Snoopers® strips are useful in characterizing lipid-binding antibodies and decoding cell signalling pathways. Ganglioside GM1 prevents the formation of aggregating cytotoxic fibrils from α-synuclein in Parkinson′s disease. The deficiency of the GM1 β-galactosidase results in the accumulation of GM1 in lysosomes leading to GM1 gangliosidosis. High levels of GM1 leads to neuronal degeneration. GM1 supplementation improves cognitive function in Alzheimer′s disease patients.
Packaging
ELISA Strip Packaged in Foil Pouch (330651-1EA)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Snoopers is a trademark of Avanti Polar Lipids, LLC
Related product
Product No.
Description
Pricing
Storage Class
12 - Non Combustible Liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Avanti lipid tools: connecting lipids, technology, and cell biology
Sims KH, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1841(8), 1038-1048 (2014)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service