W318101

2-Methoxycinnamaldehyde

natural, 98%, FG

• Synonym(s): o-Methoxycinnamaldehyde
• Linear Formula: CH₃OC₆H₄CH=CHCHO
• CAS Number: 1504-74-1
• Molecular Weight: 162.19
• FEMA Number: 3181
• EC Number: 216-131-3
• Council of Europe no.: 571
• MDL number: MFCD00007001
• UNSPSC Code: 12164502
• PubChem Substance ID: 329830575
• Flavis number: 5.048
• NACRES: NA.21

Properties

• grade: FG; Fragrance grade; Halal; Kosher; natural
• agency: follows IFRA guidelines
• reg. compliance: EU Regulation 1223/2009; EU Regulation 1334/2008 & 178/2002; FDA 21 CFR 172.515
• assay: 98%
• bp: 160-161 °C/12 mmHg (lit.)
• mp: 44.0-49.0 °C (lit.)
• application(s): flavors and fragrances
• documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• fragrance allergen: no known allergens
• organoleptic: cinnamon; woody; spicy; sweet
• SMILES string: [H]C(=O)C=Cc1ccccc1OC
• InChI: 1S/C10H10O2/c1-12-10-7-3-2-5-9(10)6-4-8-11/h2-8H,1H3/b6-4+
• InChI key: KKVZAVRSVHUSPL-GQCTYLIASA-N

Description

Application

• Network pharmacology combined with molecular docking and experimental validation to explore the potential mechanism of Cinnamomi ramulus against ankylosing spondylitis.: This study investigates the anti-inflammatory potential of 2-Methoxycinnamaldehyde in Cinnamomi ramulus. Its application extends to novel therapeutic approaches for treating ankylosing spondylitis, demonstrating significant implications for medicinal chemistry and pharmacology (Wei et al., 2023).


• Ramulus Cinnamomi essential oil exerts an anti-inflammatory effect on RAW264.7 cells through N-acylethanolamine acid amidase inhibition.: The study elaborates on the anti-inflammatory activities of 2-Methoxycinnamaldehyde, offering a biochemical pathway that could be exploited in anti-inflammatory drug design (Jia et al., 2023).
• Metabolomics-Driven Exploration of the Antibacterial Activity and Mechanism of 2-Methoxycinnamaldehyde.: This article offers insights into the antibacterial properties of 2-Methoxycinnamaldehyde, using metabolomics to explore its mechanism of action, significant for developments in antimicrobial treatments (Qian et al., 2022).

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: 235.4 °F
• flash_point_c: 113 °C