W239607

Dimethyl succinate

98%, FG

• Synonym(s): Dimethyl butanedioate, Succinic acid dimethyl ester
• Linear Formula: CH₃OCOCH₂CH₂COOCH₃
• CAS Number: 106-65-0
• Molecular Weight: 146.14
• FEMA Number: 2396
• Beilstein/REAXYS Number: 956776
• EC Number: 203-419-9
• Council of Europe no.: 439
• MDL number: MFCD00008466
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901044
• Flavis number: 9.445
• NACRES: NA.21
• organoleptic: green; fruity; floral; sweet
• grade: FG; Halal; Kosher
• biological source: synthetic
• food allergen: no known allergens

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Halal; Kosher
• reg. compliance: EU Regulation 1334/2008 & 178/2002; FDA 21 CFR 117; FDA 21 CFR 172.515
• vapor pressure: 0.3 mmHg ( 20 °C)
• assay: 98%
• autoignition temp.: 689 °F
• expl. lim.: 8.5 %
• refractive index: n20/D 1.419 (lit.)
• bp: 200 °C (lit.)
• mp: 16-19 °C (lit.)
• density: 1.117 g/mL at 25 °C (lit.)
• application(s): flavors and fragrances
• documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• organoleptic: green; fruity; floral; sweet
• SMILES string: COC(=O)CCC(=O)OC
• InChI: 1S/C6H10O4/c1-9-5(7)3-4-6(8)10-2/h3-4H2,1-2H3
• InChI key: MUXOBHXGJLMRAB-UHFFFAOYSA-N

Description

General description

Dimethyl succinate can be used as a flavoring agent in the food industry.

Application

• Metabolic Bypass Rescues Aberrant S-nitrosylation-Induced TCA Cycle Inhibition and Synapse Loss in Alzheimer′s Disease Human Neurons.: This research discusses the role of metabolic intermediates like Dimethyl succinate in bypassing biochemical blocks in Alzheimer′s disease, offering potential therapeutic avenues (Andreyev et al., 2024).


• Update to RIFM fragrance ingredient safety assessment, dimethyl succinate, CAS Registry Number 106-65-0.: A comprehensive safety assessment of Dimethyl succinate as a fragrance ingredient, highlighting its toxicological profile and safe usage parameters (Api et al., 2023).

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 201.2 °F - closed cup
• flash_point_c: 94 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter