W224820

4-Carvomenthenol

natural, ≥95%, FG

• Synonym(s): 4-Carvomenthenol, 4-Terpinenol
• Empirical Formula (Hill Notation): C₁₀H₁₈O
• CAS Number: 562-74-3
• Molecular Weight: 154.25
• FEMA Number: 2248
• EC Number: 209-235-5
• Council of Europe no.: 2229c
• MDL number: MFCD00001562
• UNSPSC Code: 12164502
• PubChem Substance ID: 24900946
• Flavis number: 2.072
• NACRES: NA.21

Properties

• grade: FG; Fragrance grade; Halal; Kosher; natural
• Quality Level: 400
• agency: follows IFRA guidelines
• reg. compliance: EU Regulation 1223/2009; EU Regulation 1334/2008 & 178/2002; FDA 21 CFR 117
• assay: ≥95%
• optical activity: [α]20/D −27°, neat
• greener alternative product characteristics: Less Hazardous Chemical Syntheses; Use of Renewable Feedstocks; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• refractive index: n20/D 1.478
• bp: 88-90 °C
• density: 0.931 g/mL at 25
• application(s): flavors and fragrances
• documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• fragrance allergen: no known allergens
• greener alternative category: Aligned
• organoleptic: herbaceous; woody; pepper
• SMILES string: CC(C)C1(O)CCC(C)=CC1
• InChI: 1S/C10H18O/c1-8(2)10(11)6-4-9(3)5-7-10/h4,8,11H,5-7H2,1-3H3
• InChI key: WRYLYDPHFGVWKC-UHFFFAOYSA-N

Description

General description

Natural occurrence: Anise, basil, black currant, cocoa, coriander, cranberry, grapefruit, lemon, lime, marjoram, peppermint oil, nutmeg and spearmint.

Application

• Quantification of six volatile oil constituents of Oleum Cinnamomi in rat plasma and multiple tissues using GC-MS and its application to pharmacokinetic and tissue distribution studies.: This study by Chi MY et al. focused on quantifying volatile oil constituents, including 4-Carvomenthenol, in rat plasma and tissues using GC-MS, providing insights into their pharmacokinetics and tissue distribution (Chi et al., 2023).


• 4-Carvomenthenol ameliorates the murine combined allergic rhinitis and asthma syndrome by inhibiting IL-13 and mucus production via p38MAPK/NF-κB signaling pathway axis.: This research by Bezerra Barros GC et al. demonstrated the anti-inflammatory effects of 4-Carvomenthenol in a murine model of allergic rhinitis and asthma, highlighting its potential therapeutic applications (Bezerra Barros et al., 2020).


• Fragrance material review on 4-carvomenthenol.: Bhatia SP et al. reviewed the use of 4-Carvomenthenol as a fragrance material, discussing its chemical properties, safety, and applications in the fragrance industry (Bhatia et al., 2008).

Biochem/physiol Actions

Taste at 30 ppm

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 174.2 °F - closed cup
• flash_point_c: 79 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter