D87201

2-Chloro-N,N-diethylethylamine hydrochloride

99%

• Synonym(s): 2-(Diethylamino)ethyl chloride hydrochloride, 2-Chlorotriethylamine hydrochloride
• Linear Formula: (C₂H₅)₂NCH₂CH₂Cl · HCl
• CAS Number: 869-24-9
• Molecular Weight: 172.10
• Beilstein/REAXYS Number: 3591991
• EC Number: 212-786-4
• MDL number: MFCD00012519
• UNSPSC Code: 12352100
• PubChem Substance ID: 24894220
• NACRES: NA.22

Properties

• assay: 99%
• form: crystals
• mp: 208-210 °C (lit.)
• SMILES string: Cl.CCN(CC)CCCl
• InChI: 1S/C6H14ClN.ClH/c1-3-8(4-2)6-5-7;/h3-6H2,1-2H3;1H
• InChI key: RAGSWDIQBBZLLL-UHFFFAOYSA-N

Description

Application

2-Chloro-N,N-diethylethylamine hydrochloride can be used as an alkylating reagent for the synthesis of:

• Substituted oxindole derivatives to be used as growth hormone secretagogs.
• 1-Substituted-5,6-dinitrobenzimidazoles with antimicrobial and antiprotozoal activities.
• Thiophene containing triarylmethane (TRAM) derivatives to be used as antitubercular agents.
• Tris(2-(diethylamino)ethyl)amine to be used as a catalyst in combination with CuBr (Et₆TREN/CuBr) for atom transfer radical polymerization of n-butyl acrylate.

It can also be used for the derivatization of chitosan to incorporate aminofunctionality onto it at C-6 position.

Safety Information

• pictograms: GHS06,GHS08,GHS05
• signalword: Danger
• hcodes: H300,H314,H341,H412
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges