D62004

cis-1,2-Dichloroethylene

97%

• Synonym(s): cis-1,2-DCE, cis-Acetylene dichloride
• Linear Formula: ClCH=CHCl
• CAS Number: 156-59-2
• Molecular Weight: 96.94
• Beilstein/REAXYS Number: 1071208
• EC Number: 205-859-7
• MDL number: MFCD00000925
• UNSPSC Code: 12352100
• PubChem Substance ID: 24894011
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• form: liquid
• refractive index: n20/D 1.449 (lit.)
• bp: 60 °C (lit.)
• mp: −80 °C (lit.)
• density: 1.284 g/mL at 25 °C (lit.)
• SMILES string: Cl\C=C/Cl
• InChI: 1S/C2H2Cl2/c3-1-2-4/h1-2H/b2-1-
• InChI key: KFUSEUYYWQURPO-UPHRSURJSA-N

Description

Application

cis-1,2-Dichloroethylene (cis-1,2-DCE) is generally used in the preparation of various enediynes for Bergman cyclization. Applications include the synthesis of:

• 2-(6-substituted 3(Z)-hexen-1,5-diynyl)anilines to prepare corresponding substituted carbazoles.
• (Z)-1-aryl-3-henen-1,5-diynes to obtain the corresponding aryl substituted benzotriazoles.

It is used as a linker to synthesize boron-dipyrromethene (BODIPY)-based photosensitizer for photodynamic therapy (PDT). cis-1,2-DCE can also be used as a precursor to synthesize intermediates of sporolide B.

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H302 + H332,H315,H412
• pcodes: P210 - P233 - P273 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2 - Skin Irrit. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 42.8 °F - closed cup
• flash_point_c: 6.0 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves