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Key Documents

C101400

Sigma-Aldrich

1,2-Cyclohexanedione

97%

Synonym(s):

1,2-Dioxocyclohexane, Cyclohexan-1,2-dione

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About This Item

Linear Formula:
C6H8(=O)2
CAS Number:
Molecular Weight:
112.13
Beilstein/REAXYS Number:
507419
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

form

solid

bp

193-195 °C (lit.)

mp

34-38 °C (lit.)

storage temp.

2-8°C

SMILES string

O=C1CCCCC1=O

InChI

1S/C6H8O2/c7-5-3-1-2-4-6(5)8/h1-4H2

InChI key

OILAIQUEIWYQPH-UHFFFAOYSA-N

Gene Information

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Application

Specific reagent for arginine residues.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves, type N95 (US)


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S Adak et al.
The Biochemical journal, 314 ( Pt 3), 985-991 (1996-03-15)
The plausible role of arginine and tyrosine residues at the active side of horseradish peroxidase (HRP) in aromatic donor (guaiacol) oxidation was probed by chemical modification followed by characterization of the modified enzyme. The arginine-specific reagents phenylglyoxal (PGO), 2,3-butanedione and
C Cervenanský et al.
European journal of biochemistry, 229(1), 270-275 (1995-04-01)
The West African green mamba, Dendroaspis angusticeps, has two toxins, fasciculins, that are non-competitive inhibitors of acetylcholinesterase. Arginine residues of fasciculin 2 were modified with 1,2-cyclohexanedione. Two of these residues, Arg24 and Arg37, reacted very slowly or not at all.
Alma Steinbach et al.
The FEBS journal, 279(7), 1209-1219 (2012-02-09)
The thiamine diphosphate (ThDP) dependent flavoenzyme cyclohexane-1,2-dione hydrolase (CDH) (EC 3.7.1.11) catalyses a key step of a novel anaerobic degradation pathway for alicyclic alcohols by converting cyclohexane-1,2-dione (CDO) to 6-oxohexanoate and further to adipate using NAD(+) as electron acceptor. To
J J Calvete et al.
FEBS letters, 444(2-3), 260-264 (1999-03-02)
PDC-109, the major heparin-binding protein of bull seminal plasma, binds to sperm choline lipids at ejaculation and modulates capacitation mediated by heparin. Affinity chromatography on heparin-Sepharose showed that polydisperse, but not monomeric, PDC-109 displayed heparin-binding capability. We sought to characterise
A Nadal et al.
The Journal of physiology, 492 ( Pt 3), 737-750 (1996-05-01)
1. When albumin from either plasma or serum is applied at low concentrations to cortical astrocytes a decrease in the level of [Ca2+]i is observed. At higher concentrations trains of calcium spikes are seen. 2. Removal of the polar lipids

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