MilliporeSigma
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A9563

Sigma-Aldrich

4-Aminophenylmercuric acetate

≥90% (titration)

Synonym(s):
APMA, 4-(Acetoxymercurio)aniline
Linear Formula:
CH3CO2HgC6H4NH2
CAS Number:
Molecular Weight:
351.75
Beilstein:
3664749
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥90% (titration)

form

powder

mp

163-165 °C (lit.)

solubility

DMSO: soluble 10 mg/mL
H2O: soluble 5 mM
glacial acetic acid: soluble 50 mg/mL

SMILES string

CC(=O)O[Hg]c1ccc(N)cc1

InChI

1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1

InChI key

RXSUFCOOZSGWSW-UHFFFAOYSA-M

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Packaging

5, 25 g in glass bottle

Biochem/physiol Actions

An organomercurial activator of matrix metalloproteinases.

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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Product Information Sheet

More Documents

Quotes and Ordering

K R French et al.
Equine veterinary journal, 36(3), 261-266 (2004-05-19)
Acute laminitis is characterised by hoof lamellar dermal-epidermal separation at the basement membrane (BM) zone. Hoof lamellar explants cultured in vitro can also be made to separate at the basement membrane zone and investigating how this occurs may give insight
Jan-Olof Winberg et al.
European journal of biochemistry, 270(19), 3996-4007 (2003-09-27)
In the leukemic macrophage cell-line THP-1, a fraction of the secreted matrix metalloproteinase 9 (MMP-9) is linked to the core protein of chondroitin sulfate proteoglycans (CSPG). Unlike the monomeric and homodimeric forms of MMP-9, the addition of exogenous CaCl2 to
Manuel Johanns et al.
Scientific reports, 7(1), 4328-4328 (2017-07-01)
Matrix metalloproteinases (MMPs) are regulated at multiple transcriptional and post-transcriptional levels, among which receptor-mediated endocytic clearance. We previously showed that low-density lipoprotein receptor-related protein-1 (LRP-1) mediates the clearance of a complex between the zymogen form of MMP-2 (proMMP-2) and tissue
A Bianchi et al.
Osteoarthritis and cartilage, 24(11), 1961-1969 (2016-10-21)
Fibroblast Growth Factor 23 (FGF23) may represent an attractive candidate that could participate to the osteoarthritic (OA)-induced phenotype switch of chondrocytes. To address this hypothesis, we investigated the expression of FGF23, its receptors (FGFRs) and co-receptor (Klotho) in human cartilage
Tobias M J Allinson et al.
European journal of biochemistry, 271(12), 2539-2547 (2004-06-09)
Numerous transmembrane proteins, including the blood pressure regulating angiotensin converting enzyme (ACE) and the Alzheimer's disease amyloid precursor protein (APP), are proteolytically shed from the plasma membrane by metalloproteases. We have used an antisense oligonucleotide (ASO) approach to delineate the

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