908517
Poly(D,L-lactide-b-glycolide) lactide:glycolide 50:50
amine terminated, average Mn 5,000
Synonym(s):
Amino-PLGA, Amino-functionalized PLGA, AminoPLGA, NH2 PLGA, PLGA-NH2
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About This Item
Linear Formula:
C2H7N2(C3H4O2)x(C2H2O2)yH
UNSPSC Code:
12162002
NACRES:
NA.23
Recommended Products
form
powder or chunks
feed ratio
lactide:glycolide 50:50
mol wt
average Mn 5,000
color
white to tan
storage temp.
−20°C
Application
Biocompatible and biodegradable polymer can be used in the formation of nanoparticles for drug delivery. The amine functional group enables rapid and facile surface functionalization, allowing for this material to be used in applications such as targeted drug delivery.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Yihan Xu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 105(6), 1692-1716 (2016-04-22)
Poly (lactic-co-glycolic acid) (PLGA) copolymers have been broadly used in controlled drug release applications. Because these polymers are biodegradable, they provide an attractive option for drug delivery vehicles. There are a variety of material, processing, and physiological factors that impact
R Gref et al.
Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these
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