901361
N-((Methylsulfonyl)oxy)acetimidoyl chloride
≥95%
Synonym(s):
(1-Chloroethylidene)azanyl ester methanesulfonic acid
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Application
This air- and moisture-stable reagent enables the direct functionalization of pyridines under mild conditions for late-stage diversification of complex and drug-like molecules.
Storage Class
4.1B - Flammable solid hazardous materials
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Journal of the American Chemical Society, 139(28), 9499-9502 (2017-07-06)
Herein is reported the design and application of a reagent for the direct functionalization of pyridines. These reactions occur under mild conditions and exhibit broad functional group tolerance, enabling the late-stage functionalization of drug-like molecules. The reagent can be easily
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