856088

β-Cyclodextrin hydrate

99%

• Synonym(s): beta-Cyclodextrin hydrate, β-Schardinger dextrin, Cycloheptaamylose, Schardinger β-Dextrin hydrate
• Empirical Formula (Hill Notation): C₄₂H₇₀O₃₅ · xH₂O
• CAS Number: 68168-23-0
• Molecular Weight: 1134.98 (anhydrous basis)
• EC Number: 231-493-2
• MDL number: MFCD00150811
• UNSPSC Code: 12352005
• PubChem Substance ID: 329769393
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: 99%
• form: solid
• optical activity: [α]20/D +142°, c = 1 in H₂O (Dry basis)
• mp: >260 °C (dec.) (lit.)
• functional group: ether
• SMILES string: O.OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]8CO)O[C@H]1[C@H](O)[C@H]2O
• InChI: 1S/C42H70O35.H2O/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51;/h8-63H,1-7H2;1H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-;/m1./s1
• InChI key: JNSAKCOAFBFODP-ZQOBQRRWSA-N

Description

General description

β-cyclodextrin (β-CD), a well-known macrocyclic oligosaccharide member of the CD family, is composed of seven D-glucose units connected via α(1→4) glycosidic bonds. Its ability to form several inclusion complexes with organic as well as inorganic compounds makes it a potential candidate in solid and solution state determinations.

Application

β-Cyclodextrin hydrate may be used:

• To form an inclusion complex with norfloxacin for subsequent analysis using high performance liquid chromatography (HPLC).
• As a precursor of heptakis-(2,3-diacetyl-6-sulfato)-β-cyclodextrin for use as a chiral selector in the enantioseparation of linezolid by capillary electrophoresis (CE).

Forms clathrates. Produces a water-soluble complex with dansyl chloride (cat. no. D143359) for the fluorescent labeling of proteins.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• ppe: Eyeshields, Gloves, type N95 (US)