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735809

Sigma-Aldrich

[2-(Di-tert-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine]carbonylchlorohydridoruthenium(II)

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Synonym(s):

Milstein Catalyst Precursor, [2-(Di-tert-butylphosphinomethyl)-6-(diethylaminomethyl)pyridine]ruthenium(II) chlorocarbonyl hydride

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About This Item

Empirical Formula (Hill Notation):
C20H36ClN2OPRu
CAS Number:
863971-62-4
Molecular Weight:
488.01
MDL number:
MFCD16038117
UNSPSC Code:
12352300
PubChem Substance ID:
329765059
NACRES:
NA.22

form

powder

reaction suitability

core: ruthenium
reagent type: catalyst

greener alternative product characteristics

Catalysis
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Aligned,

SMILES string

Cl[RuH].[C-]#[O+].CCN(CC)Cc1cccc(CP(C(C)(C)C)C(C)(C)C)n1

InChI

1S/C19H35N2P.CO.ClH.Ru.H/c1-9-21(10-2)14-16-12-11-13-17(20-16)15-22(18(3,4)5)19(6,7)8;1-2;;;/h11-13H,9-10,14-15H2,1-8H3;;1H;;/q;;;+1;/p-1

InChI key

RZCAJPSOQUIHSH-UHFFFAOYSA-M

General description

May contain up to 10% acetone and/or THF.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Application

Precursor to active Ru catalyst for the dehydrogenative coupling of amines and alcohols to form amide bonds.
Precursor to active ruthenium catalyst for greener amide bond formation by dehydrogenative coupling of amines and alcohols.

Direct Synthesis of Amides from Alcohols and Amines with Liberation of H2

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

hcodes

H319,H351

Hazard Classifications

Carc. 2 - Eye Irrit. 2

supp_hazards

EUH019

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SHBJ9886
07896APV
07896AP

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Articles

Ester Hydrogenation

Learn about Ester Hydrogenation from MilliporeSigma. The reduction of esters to alcohols is typically accomplished using metal hydrides. While effective, it comes at the cost of stoichiometric waste and complicated workup procedures.

Greener Methods: Catalytic Amide Bond Formation

We are proud to offer a number of products used in catalytic amidation technology.

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