710385

Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine

95%

• Empirical Formula (Hill Notation): C₁₈H₂₂ClO₂P
• CAS Number: 136802-85-2
• Molecular Weight: 336.79
• MDL number: MFCD01630810
• UNSPSC Code: 12352112
• PubChem Substance ID: 329762920
• NACRES: NA.22

Properties

• assay: 95%
• form: liquid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• refractive index: n20/D 1.597
• density: 1.141 g/cm³ at 25 °C
• functional group: phosphine
• SMILES string: COc1c(C)cc(cc1C)P(Cl)c2cc(C)c(OC)c(C)c2
• InChI: 1S/C18H22ClO2P/c1-11-7-15(8-12(2)17(11)20-5)22(19)16-9-13(3)18(21-6)14(4)10-16/h7-10H,1-6H3
• InChI key: JWCZKGYRAINWJA-UHFFFAOYSA-N

Description

Application

Reactant for:

• Asymmetric organocatalytic electrophilic phosphination
• Asymmetric hydroformulation using Taddol-based chiral phosphine-phosphite ligands
• Synthesis of ferrocene-based chiral diphosphines
• Alcoholysis of phosphane-boranes
• Asymmetric hydrogenations of bifep-type biferrocenes

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P305 + P351 + P338 - P310
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable