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Key Documents

707230

Sigma-Aldrich

tert-Butyldichlorophosphine solution

1.0 M in diethyl ether

Synonym(s):

(1,1-Dimethylethyl)phosphonous dichloride solution

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About This Item

Empirical Formula (Hill Notation):
C4H9Cl2P
CAS Number:
Molecular Weight:
158.99
MDL number:
UNSPSC Code:
12352001
PubChem Substance ID:
NACRES:
NA.22

form

liquid

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

concentration

1.0 M in diethyl ether

density

0.766 g/mL at 25 °C

functional group

phosphine

SMILES string

CC(C)(C)P(Cl)Cl

InChI

1S/C4H9Cl2P/c1-4(2,3)7(5)6/h1-3H3

InChI key

NMJASRUOIRRDSX-UHFFFAOYSA-N

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Application

Reactant for:
  • The preparation of Buchwald-type secondary phosphine oxide ligands
  • Asymmetric hydrogenation

Reactant for the synthesis of:
  • Alkali metal complexes
  • P-Stereogenic compounds via kinetic deprotonation
  • Ortho-trifluoromethylphenyl-substituted phosphines

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 1 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

supp_hazards

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3


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