637386

6-Chloro-3-pyridinylboronic acid

≥95.0%

• Synonym(s): 2-Chloro-5-pyridineboronic acid
• Empirical Formula (Hill Notation): C₅H₅BClNO₂
• CAS Number: 444120-91-6
• Molecular Weight: 157.36
• MDL number: MFCD03094998
• UNSPSC Code: 12352103
• PubChem Substance ID: 24882850
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥95.0%
• form: solid
• mp: 165 °C (lit.)
• functional group: chloro
• SMILES string: OB(O)c1ccc(Cl)nc1
• InChI: 1S/C5H5BClNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3,9-10H
• InChI key: WPAPNCXMYWRTTL-UHFFFAOYSA-N

Description

Application

6-Chloro-3-pyridinylboronic acid can be used:

• To prepare biologically significant 3-arylcoumarins by reacting with 3-chlorocoumarin through Suzuki reaction.
• As a substrate in the synthesis of 11-(pyridinylphenyl)steroid with progesterone agonist/antagonist profile.
• As a substrate in the preparation of α- secondary and tertiary pyridines by the reaction of pyridotriazoles with boronic acids.
• As a substrate in the palladium-catalyzed α-arylation of saturated cyclic amines and N-methyl amines.

Other Notes

Contains varying amounts of anhydride

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves