574686

3-Aminophenylboronic acid pinacol ester

97%

• Synonym(s): 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
• Empirical Formula (Hill Notation): C₁₂H₁₈BNO₂
• CAS Number: 210907-84-9
• Molecular Weight: 219.09
• MDL number: MFCD03453668
• UNSPSC Code: 12352103
• PubChem Substance ID: 24880752
• NACRES: NA.22

Properties

• assay: 97%
• mp: 90-94 °C (lit.)
• SMILES string: CC1(C)OB(OC1(C)C)c2cccc(N)c2
• InChI: 1S/C12H18BNO2/c1-11(2)12(3,4)16-13(15-11)9-6-5-7-10(14)8-9/h5-8H,14H2,1-4H3
• InChI key: YMXIIVIQLHYKOT-UHFFFAOYSA-N

Description

Application

3-Aminophenylboronic acid pinacol ester can be used:

• As a starting material for the synthesis of 6-(hetero)arylthieno[3,2-b]pyridines, which are known to inhibit human tumor cells selectively.
• In the functionalization of deuteroporphyrin IX dimethyl ester through Suzuki-Miyaura coupling.
• To prepare benzo[d]oxazole based type-I FLT3-ITD inhibitors.

Legal Information

Product of Boron Molecular

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves