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Diethyl azodicarboxylate solution

40 wt. % in toluene

NSC 679015, Diethoxycarbonyldiazene solution, NSC 3474, DEAD, Unifoam AZ-AE 200, Diethyl azodiformate solution, 1,2-Ethoxycarbonyl diazene solution
Linear Formula:
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:

Quality Level


40 wt. % in toluene

refractive index

n20/D 1.4690


116-117 °C


0.956 g/mL at 25 °C

storage temp.


SMILES string




InChI key


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General description

DOT Special Approval Submission is Under Review. Availability is Estimated as March 2012.


Reactant for preparation of:
  • Immunostimulants α-Galactosylceramides
  • Cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases
  • Bisubstrate inhibitors with molecular recognition at the active site of catechol-O-methyltransferase
  • Derivatives of F200 and S383 with cannabinoid CB1 receptor binding activities
  • Aza-β-lactams via NHC-catalyzed [2 + 2] cycloaddition with ketenes

Reagent for:
  • Annulation of N-protected imines
  • α-thiocyanation of enolizable ketones with ammonium thiocyanate
  • Diels-Alder reactions
A commonly used activating reagent in Mitsunobo reactions.


25, 100 g in glass bottle
100g unit contains ca. 40g DEAD solute
25g unit contains ca. 10g DEAD solute


Toxic, Irritant, Flammable

Signal Word


Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 2 - Self-react. C - Skin Irrit. 2 - STOT RE 2

Target Organs

Central nervous system

Storage Class Code

4.1A - Other explosive hazardous materials



Flash Point(F)

105.8 °F - closed cup

Flash Point(C)

41 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

A Fürstner et al.
The Journal of organic chemistry, 65(6), 1738-1742 (2000-04-06)
A concise synthesis of the hexahydroazepine moiety 13 of (-)-balanol 1 is described that comprises only eight steps and is distinctly shorter than all previous reported approaches to this particular compound. Sharpless epoxidation of divinylcarbinol 4 and ring closing alkene
Fany Reffuveille et al.
Antimicrobial agents and chemotherapy, 58(9), 5363-5371 (2014-07-02)
Biofilm-related infections account for at least 65% of all human infections, but there are no available antimicrobials that specifically target biofilms. Their elimination by available treatments is inefficient since biofilm cells are between 10- and 1,000-fold more resistant to conventional
Adrian Egli et al.
The Journal of infectious diseases, 210(5), 717-727 (2014-03-13)
Feedback mechanisms between interferons α and λ (IFNs) may be affected by single nucleotide polymorphisms (SNP) in interleukin 28B (IL-28B; IFN-λ3) promoter region and may influence cytomegalovirus (CMV) replication. We associated IL-28B SNPs with the risk of CMV replication after
Jetze Visser et al.
Nature communications, 6, 6933-6933 (2015-04-29)
Despite intensive research, hydrogels currently available for tissue repair in the musculoskeletal system are unable to meet the mechanical, as well as the biological, requirements for successful outcomes. Here we reinforce soft hydrogels with highly organized, high-porosity microfibre networks that
A Ranga et al.
Nature communications, 5, 4324-4324 (2014-07-17)
The behaviour of mammalian cells in a tissue is governed by the three-dimensional (3D) microenvironment and involves a dynamic interplay between biochemical and mechanical signals provided by the extracellular matrix (ECM), cell-cell interactions and soluble factors. The complexity of the

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