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534498

Sigma-Aldrich

4-Piperidinopiperidine

97%

Synonym(s):

1,4′-Bipiperidine

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About This Item

Empirical Formula (Hill Notation):
C10H20N2
CAS Number:
4897-50-1
Molecular Weight:
168.28
EC Number:
225-522-8
MDL number:
MFCD00006475
UNSPSC Code:
12352100
PubChem Substance ID:
24878040
NACRES:
NA.22

assay

97%

mp

64-66 °C (lit.)

storage temp.

−20°C

SMILES string

C1CCN(CC1)C2CCNCC2

InChI

1S/C10H20N2/c1-2-8-12(9-3-1)10-4-6-11-7-5-10/h10-11H,1-9H2

InChI key

QDVBKXJMLILLLB-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

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Related Categories

Application

Reactant for synthesis of:
Arylthiadiazole H3 antagonists
Water-soluble N-mustards as anticancer agents
Antitubercular drugs
Vasopressin1b receptor antagonists
MDR modulators
Selective Norepinephrine transporter inhibitors
Medicinal chemistry reagent.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Synlett, 8, 1192-1194 (2003)
Hidetsura Cho et al.
Journal of medicinal chemistry, 47(1), 101-109 (2003-12-30)
A variety of novel heterocyclic compounds having thienoazepine, pyrroloazepine, furoazepine, and thienodiazepine skeletons were synthesized, most of which exhibited potent antagonism of [(3)H]-AVP specific binding in assays using rat liver (V1), rat kidney (V2), human platelet plasma membranes, and recombinant
José M Quintela et al.
European journal of medicinal chemistry, 38(3), 265-275 (2003-04-02)
New antiprotozoals active against Philasterides dicentrarchi, the causative agent of scuticociliatosis in farmed turbot and Black Sea bass-bream, have been synthesised and tested. The most active compounds posses a piperazine ring, generally N-bonded to the heterocycle, and are the 1,8-naphthyridines
A W McConnaughie et al.
Journal of medicinal chemistry, 37(8), 1063-1069 (1994-04-15)
As as initial step in the design of structure-specific RNA-interactive molecules as potential antiviral agents, we have focused on the synthesis of molecules that exhibit strong and preferential binding to duplex RNA. A series of polycationic ligands have been synthesized
Yuqiang Wang et al.
Bioorganic & medicinal chemistry, 13(19), 5592-5599 (2005-08-09)
We have synthesized a conjugate of cis-4,7,10,13,16,19-docosahexenoic acid (DHA) and 10-hydroxycamptothecin (HCPT), DHA-HCPT. The antitumor activity of DHA-HCPT was evaluated in vitro against L1210 leukemia cells and in experimental animal tumor models including L1210 leukemia, Lewis lung carcinoma, and colon
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