Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

View All Documentation

481858

Sigma-Aldrich

Methyl p-tolyl sulfoxide

97%

Synonym(s):

(±)-Methyl p-toluene sulfoxide, (±)-p-Tolyl methyl sulfoxide, 1-Methanesulfinyl-4-methylbenzene, 1-Methyl-4-(methylsulfinyl)benzene, 4-(Methylsulfinyl)toluene, 4-Methylphenyl methyl sulfoxide, 4-Toluene methyl sulfoxide, Methyl 4-methylphenyl sulfoxide, p-Methylphenyl methyl sulfoxide, p-Tolyl methyl sulfoxide

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
CH3C6H4S(O)CH3
CAS Number:
934-72-5
Molecular Weight:
154.23
MDL number:
MFCD00075175
UNSPSC Code:
12352100
PubChem Substance ID:
24871787
NACRES:
NA.22

assay

97%

bp

113-114 °C/2 mmHg (lit.)

mp

44-46 °C (lit.)

functional group

sulfoxide

SMILES string

Cc1ccc(cc1)S(C)=O

InChI

1S/C8H10OS/c1-7-3-5-8(6-4-7)10(2)9/h3-6H,1-2H3

InChI key

FEVALTJSQBFLEU-UHFFFAOYSA-N

Related Categories

General description

Methyl p-tolyl sulfoxide (MTSO), an alkyl-substituted p-tolyl sulfoxide, is a Lewis base. It behaves as an activator of silicon tetrachloride that is employed in aza-Diels-Alder reaction.

Application

Methyl p-tolyl sulfoxide may be used as a catalyst in the preparation of homoallylic alcohols by the allylation of aldehydes with allyltrichlorosilane. It may be used as a ligand in the synthesis of molybdenum chlorocomplexes.

Caution

Low melting solid

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BGBC4729V
BGBC3007V
BGBC1858V
MKBJ6966V
MKBC1041V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 3

1 of 3

DEET PESTANAL®, analytical standard

Supelco

36542

DEET

Methyl phenyl sulfone ≥98.0% (GC)

Sigma-Aldrich

68742

Methyl phenyl sulfone

Peracetic acid solution 32 wt. % in dilute acetic acid

Sigma-Aldrich

269336

Peracetic acid solution

Luisa A Denkel et al.
PloS one, 6(11), e26974-e26974 (2011-11-11)
Production of reactive oxygen species represents a fundamental innate defense against microbes in a diversity of host organisms. Oxidative stress, amongst others, converts peptidyl and free methionine to a mixture of methionine-S- (Met-S-SO) and methionine-R-sulfoxides (Met-R-SO). To cope with such
Addition compounds of MoO2Cl2 with chiral sulfoxides. First molecular structures of dioxomolybdenum complexes bearing chiral non-racemic sulfoxide as ligand.
Pedrosa MR, et al.
Inorgorganica Chimica Acta, 363(13), 3158-3164 (2010)
A New Approach to Di-and Tetrasubstituted 2,3-Dihydropyridin-4(1H)-ones through Aza-Diels-Alder Reaction Promoted by Silicon Tetrachloride.
Peduto A, et al.
Synthesis, 4, 0643-0649 (2009)
Asymmetric allylation of aldehydes with allyltrichlorosilane promoted by chiral sulfoxides.
Massa A, et al.
Tetrahedron Letters, 44(38), 7179-7181 (2003)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service