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451088

Sigma-Aldrich

6-Mercapto-1-hexanol

97%

Synonym(s):

6-Hydroxy-1-hexanethiol, 6-MCH, 6-Mercaptohexan-1-ol, 6-Mercaptohexanol, MCH

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About This Item

Linear Formula:
HS(CH2)6OH
CAS Number:
1633-78-9
Molecular Weight:
134.24
Beilstein/REAXYS Number:
1846871
MDL number:
MFCD00068552
UNSPSC Code:
12352103
PubChem Substance ID:
24868602
NACRES:
NA.23

assay

97%

reaction suitability

reagent type: linker

refractive index

n20/D 1.486 (lit.)

bp

225 °C (lit.)

density

0.981 g/mL at 25 °C (lit.)

functional group

hydroxyl
thiol

SMILES string

SCCCCCCO

InChI

1S/C6H14OS/c7-5-3-1-2-4-6-8/h7-8H,1-6H2

InChI key

UGZAJZLUKVKCBM-UHFFFAOYSA-N

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General description

6-mecapto-1-hexanol (MCH) forms a self-assembled monolayer (SAM) with identically represented C6 spacer. MCH is a tool for surface coating that enables blocking of active sites and non-specific absorption.

Application

MCH is coated on a piezoelectric crystal which can be used for the fabrication of chemical sensor to differentiate between cheese varieties. Self assembled monolayers of MCH can be used on gold surfaces for bio-sensing applications. It can also be used as a monolayer for the surface modification of gold-polyaniline (Au-PANI) nanocomposites for the development of aptamer based biosensors (aptasensors).

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
BGBC3274V
BGBC2287V
BGBB9865
BGBB8898
BGBB8451

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Aptamer-based microcantilever array biosensor for detection of fumonisin B-1.
Chen X, et al.
Royal Society of Chemistry Advances, 5(45), 35448-35452 (2015)
A Microelectrode Array with Reproducible Performance Shows Loss of Consistency Following Functionalization with a Self-Assembled 6-Mercapto-1-hexanol Layer.
Corrigan D, et al.
Sensors, 18(6), 1891-1891 (2018)
Surface-enhanced Raman spectroscopic study of DNA and 6-mercapto-1-hexanol interactions using large area mapping.
Frohling KB, et al.
Vibrational Spectroscopy, 86, 331-336 (2016)
Dhésmon Lima et al.
Bioelectrochemistry (Amsterdam, Netherlands), 133, 107447-107447 (2020-02-02)
Apolipoprotein E4 (ApoE4) has a key role on the onset and progression of Alzheimer's disease (AD), since it favours the deposition of toxic amyloid-beta (Aβ) aggregates in the brain. These effects might result from the interaction between ApoE4 and specific
DNA technology for small molecules sensing: a new approach for Acetamiprid detection.
AISEM Annual Conference, 2015 XVIII, 18(6), 1-4 (2015)
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Articles

Micro and Nanometer Scale Photopatterning of Self-Assembled Monolayers

Self-assembled monolayers (SAMs) have attracted enormous interest for a wide variety of applications in micro- and nano-technology. In this article, we compare the benefits of three different classes of SAM systems (alkylthiolates on gold.

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