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451088

Sigma-Aldrich

6-Mercapto-1-hexanol

97%

Synonym(s):
6-Hydroxy-1-hexanethiol, 6-Mercaptohexan-1-ol, MCH, 6-MCH, 6-Mercaptohexanol
Linear Formula:
HS(CH2)6OH
CAS Number:
Molecular Weight:
134.24
Beilstein:
1846871
MDL number:
PubChem Substance ID:
NACRES:
NA.23

assay

97%

reaction suitability

reagent type: cross-linking reagent

refractive index

n20/D 1.486 (lit.)

bp

225 °C (lit.)

density

0.981 g/mL at 25 °C (lit.)

SMILES string

SCCCCCCO

InChI

1S/C6H14OS/c7-5-3-1-2-4-6-8/h7-8H,1-6H2

InChI key

UGZAJZLUKVKCBM-UHFFFAOYSA-N

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General description

6-mecapto-1-hexanol (MCH) forms a self-assembled monolayer (SAM) with identically represented C6 spacer. MCH is a tool for surface coating that enables blocking of active sites and non-specific absorption.

Application

MCH is coated on a piezoelectric crystal which can be used for the fabrication of chemical sensor to differentiate between cheese varieties. Self assembled monolayers of MCH can be used on gold surfaces for bio-sensing applications. It can also be used as a monolayer for the surface modification of gold-polyaniline (Au-PANI) nanocomposites for the development of aptamer based biosensors (aptasensors).

Packaging

5, 25 mL in glass bottle

Storage Class Code

10 - Combustible liquids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

A Microelectrode Array with Reproducible Performance Shows Loss of Consistency Following Functionalization with a Self-Assembled 6-Mercapto-1-hexanol Layer.
Corrigan D, et al.
Sensors, 18(6), 1891-1891 (2018)
Aptamer-based microcantilever array biosensor for detection of fumonisin B-1.
Chen X, et al.
Royal Society of Chemistry Advances, 5(45), 35448-35452 (2015)
Surface-enhanced Raman spectroscopic study of DNA and 6-mercapto-1-hexanol interactions using large area mapping.
Frohling KB, et al.
Vibrational Spectroscopy, 86, 331-336 (2016)
Self-assembled monolayers of 6-mercapto-1-hexanol and mercapto-n-hexyl-poly (dT) 18-fluorescein on polycrystalline gold surfaces: An electrochemical impedance spectroscopy study.
Rivera-Gandia J and Cabrera CR
Journal of Electroanalytical Chemistry, 605(2), 145-150 (2007)
DNA technology for small molecules sensing: a new approach for Acetamiprid detection.
AISEM Annual Conference, 2015 XVIII, 18(6), 1-4 (2015)

Articles

Micro and Nanometer Scale Photopatterning of Self-Assembled Monolayers

Self-assembled monolayers (SAMs) have attracted enormous interest for a wide variety of applications in micro- and nano-technology. In this article, we compare the benefits of three different classes of SAM systems (alkylthiolates on gold.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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