417041

S-Alpine-Borane^®

97%

• Synonym(s): B-Isopinocampheyl-9-borabicyclo[3.3.1]nonane
• Empirical Formula (Hill Notation): C₁₈H₃₁B
• CAS Number: 42371-63-1
• Molecular Weight: 258.25
• MDL number: MFCD00082390
• UNSPSC Code: 12352000
• PubChem Substance ID: 24866117

Properties

• assay: 97%
• optical activity: [α]22/D +20°, c = 12 in THF
• bp: >55 °C (lit.)
• density: 0.947 g/mL at 25 °C (lit.)
• SMILES string: C[C@@H]1[C@H](CC2CC1C2(C)C)B3C4CCCC3CCC4
• InChI: 1S/C18H31B/c1-12-16-10-13(18(16,2)3)11-17(12)19-14-6-4-7-15(19)9-5-8-14/h12-17H,4-11H2,1-3H3/t12-,13+,14-,15+,16-,17-/m0/s1
• InChI key: VCDGSBJCRYTLNU-NEXGVSGLSA-N

Description

General description

S-Alpine-Borane^® is a chiral reducing agent, synthesized from (-)-α-pinene via hydroboration.

Application

S-Alpine-Borane^® may be used in the preparation of (-)-(4S)-5-methyl-2-hexyn-4-ol, an intermediate for the synthesis of (+)-Prelog-Djerassi lactonic aldehyde.

Legal Information

Alpine-Borane is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02
• signalword: Danger
• hcodes: H250
• pcodes: P222 - P231 - P422
• Hazard Classifications: Pyr. Liq. 1
• Storage Class: 4.2 - Pyrophoric and self-heating hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter