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408425

Sigma-Aldrich

Boc-Met-OH

99%

Synonym(s):

N-(tert-Butoxycarbonyl)-L-methionine, Boc-L-methionine

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About This Item

Linear Formula:
CH3SCH2CH2CH(COOH)NHCOOC(CH3)3
CAS Number:
2488-15-5
Molecular Weight:
249.33
Beilstein/REAXYS Number:
1727869
EC Number:
219-639-3
MDL number:
MFCD00065586
UNSPSC Code:
12352209
PubChem Substance ID:
24865567
NACRES:
NA.22

assay

99%

optical activity

[α]20/D −22°, c = 1 in methanol

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

47-50 °C (lit.)

application(s)

peptide synthesis

SMILES string

CSCC[C@H](NC(=O)OC(C)(C)C)C(O)=O

InChI

1S/C10H19NO4S/c1-10(2,3)15-9(14)11-7(8(12)13)5-6-16-4/h7H,5-6H2,1-4H3,(H,11,14)(H,12,13)/t7-/m0/s1

InChI key

IMUSLIHRIYOHEV-ZETCQYMHSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCD5338
BCBV7358
BCBQ6924V
BCBL2577V
BCBH1175V

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Curcumin, the principal curcuminoid of the popular Indian spice turmeric, has a wide spectrum of pharmaceutical properties such as antitumor, antioxidant, antiamyloid, and anti-inflammatory activity. However, poor aqueous solubility and low bioavailability of curcumin is a major challenge in its
Griet Van Zeebroeck et al.
Nature chemical biology, 5(1), 45-52 (2008-12-09)
Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting transceptors is unknown. We have screened 319 amino acid analogs to identify compounds that act on Gap1

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