391956

Dimethylamine solution

2.0 M in THF

• Synonym(s): N,N-Dimethylamine
• Linear Formula: (CH₃)₂NH
• CAS Number: 124-40-3
• Molecular Weight: 45.08
• Beilstein/REAXYS Number: 605257
• MDL number: MFCD00008288
• UNSPSC Code: 12352116
• PubChem Substance ID: 24864412
• NACRES: NA.22

Properties

• form: liquid
• concentration: 1.90-2.20 M (by NaOH, titration); 2.0 M in THF
• bp: ~60 °C
• density: 0.85 g/mL at 25 °C
• SMILES string: CNC
• InChI: 1S/C2H7N/c1-3-2/h3H,1-2H3
• InChI key: ROSDSFDQCJNGOL-UHFFFAOYSA-N

Description

Application

Dimethylamine solution (2M in THF) has been used in the synthesis of 2-dimethylamino-1-(3,4-methylenedioxyphenyl)propan-1-one (bk-MDDMA) , a β-keto derivative of 3,4-methylenedioxyamphetamine (MDA) by reacting with 2-bromo-3′,4′-methylenedioxypropiophenone. It may also be used to synthesize organic intermediates such as dimethyl-(4-nitro-benzyl)-amine, dimethyl-(4-methyl-benzyl)-amine and 4-dimethylamino-but-2-enoic acid [4-(3,4-dichloro-6-fluoro-phenylamino)-quinazolin-6-yl]-amide.

Safety Information

• pictograms: GHS02,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H302,H315,H318,H335,H336,H351
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Central nervous system, Respiratory system
• supp_hazards: EUH019
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: -32.8 °F - closed cup
• flash_point_c: -36 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves