388440

2-Hydroxymethyl-18-crown-6

95%

• Synonym(s): 1,4,7,10,13,16-Hexaoxacyclooctadecane-2-methanol, 18-Crown-6-methanol
• Empirical Formula (Hill Notation): C₁₃H₂₆O₇
• CAS Number: 70069-04-4
• Molecular Weight: 294.34
• Beilstein/REAXYS Number: 4313301
• EC Number: 274-299-3
• MDL number: MFCD00188046
• UNSPSC Code: 12352005
• PubChem Substance ID: 24864229
• NACRES: NA.22

Properties

• assay: 95%
• form: liquid
• refractive index: n20/D 1.479 (lit.)
• bp: 150 °C/0.5 mmHg (lit.)
• density: 1.174 g/mL at 25 °C (lit.)
• SMILES string: OCC1COCCOCCOCCOCCOCCO1
• InChI: 1S/C13H26O7/c14-11-13-12-19-8-7-17-4-3-15-1-2-16-5-6-18-9-10-20-13/h13-14H,1-12H2
• InChI key: HFRGASADQCZXHH-UHFFFAOYSA-N

Description

Application

• Stability Constants of Complexes of Crown Ether Surfactant with Several Kinds of Alkali Metal Cations: This study highlights the interaction of 2-Hydroxymethyl-18-crown-6 with different alkali metals, providing useful data for drug discovery chemists looking at ion transport mechanisms (R Kondo et al., 2023).
• Direct in situ labeling of target drugs with a fluorophore probe to improve MALDI-MS detection sensitivity in micro-liter plasma: Relevant for material science, this paper discusses the use of 2-Hydroxymethyl-18-crown-6 in enhancing detection sensitivity through mass spectrometry, a crucial technique in material analysis (YS Li, CY Lu, 2019).
• Design of crown ether based micelles and their anti-tumor properties by perturbing potassium ion homeostasis: This article could be particularly intriguing for drug discovery chemists as it links the design of crown ether-based micelles with potential therapeutic applications (L Pang et al., 2021).
• Development of effective potassium acetate extractant: Discusses the use of 2-Hydroxymethyl-18-crown-6 in the design of effective ion extractants, relevant for those in academia studying ion exchange processes (M Zakrzewski et al., 2021).

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter