Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

359505

Sigma-Aldrich

7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene

98%

Synonym(s):

1,3,4,6,7,8-Hexahydro-1-methyl-2H-pyrimido[1,2-a]pyrimidine, MTBD

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C8H15N3
CAS Number:
84030-20-6
Molecular Weight:
153.22
Beilstein/REAXYS Number:
7635759
EC Number:
281-791-1
MDL number:
MFCD00043004
UNSPSC Code:
12352100
PubChem Substance ID:
24862083
NACRES:
NA.22

Quality Level

200

assay

98%

form

liquid

refractive index

n20/D 1.537 (lit.)

bp

75-79 °C/0.1 mmHg (lit.)

density

1.067 g/mL at 25 °C (lit.)

SMILES string

CN1CCCN2CCCN=C12

InChI

1S/C8H15N3/c1-10-5-3-7-11-6-2-4-9-8(10)11/h2-7H2,1H3

InChI key

OEBXWWBYZJNKRK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene is a soluble amine base. It forms 1:1 complexes with 4-nitrophenyl[bis(diethylsulfonyl)]methane and phenyl[bis(diethylsulfonyl)]methane and their structures have been studied by FT-IR, 1H NMR and PM5 semiempirical methods. Catalytic performance of 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene for the transesterification of rapseed oil with methanol has been investigated.

Application

7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene may be used in microwave-promoted, palladium-catalyzed C-N bond-forming reactions with aryl/heteroaryl nonaflates and amines. It may be used as strong base to investigate the podand solvents, tris(oxaalkyl)phenylsilanes and tris(oxaalkyl)phosphates.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCB0589
BCBP4663V
BCBM2491V
BCBB0781V
BCBB0781

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Transesterification of vegetable oils: a review.
Schuchardt U, et al.
Journal of the Brazilian Chemical Society, 9(3), 199-210 (1998)
Rachel E Tundel et al.
The Journal of organic chemistry, 71(1), 430-433 (2006-01-04)
[reaction: see text] Microwave-assisted, palladium-catalyzed C-N bond-forming reactions with aryl/heteroaryl nonaflates and amines using the soluble amine bases DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) or MTBD (7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene) and ligands (1-3) resulted in good to excellent yields (71-99%) of arylamines in short reaction times (1-45
Podand solvents for organic reactions.
Gierczyk B, et al.
Supramolecular Chemistry, 14(6), 497-502 (2002)
Spectroscopic studies of the 1: 1 complexes of 4-nitrophenyl [bis (ethylsulfonyl)] methane and phenyl [bis (ethylsulfonyl)] methane with 7-methyl-1, 5, 7-triazabicyclo [4.4. 0] dec-5-ene and 1, 5, 7-triazabicyclo [4.4. 0] dec-5-ene.
Huczynski A, et al.
Journal of Molecular Structure, 841(1), 133-136 (2007)
Jiun-Min Hsu et al.
PLoS genetics, 10(11), e1004715-e1004715 (2014-11-14)
Neuronal cargos are differentially targeted to either axons or dendrites, and this polarized cargo targeting critically depends on the interaction between microtubules and molecular motors. From a forward mutagenesis screen, we identified a gain-of-function mutation in the C. elegans α-tubulin

Articles

Deoxyfluorination with 2-Pyridinesulfonyl Fluoride (PyFluor)

The prevalence of organofluorine compounds in industry and drug design necessitates the ability to introduce C–F bonds to molecules.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service