345482

Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate

98%

• Synonym(s): α,β-Isopropylidene-D-glyceric acid methyl ester, Methyl α,β-isopropylidene-D-glycerate, Methyl 2,3-O-isopropylidene-D-glycerate
• Empirical Formula (Hill Notation): C₇H₁₂O₄
• CAS Number: 52373-72-5
• Molecular Weight: 160.17
• Beilstein/REAXYS Number: 4292353
• MDL number: MFCD00066527
• UNSPSC Code: 12352005
• PubChem Substance ID: 24861325
• NACRES: NA.22

Properties

• assay: 98%
• form: liquid
• optical activity: [α]20/D +8.5°, c = 1.5 in acetone
• refractive index: n20/D 1.426 (lit.)
• bp: 70-75 °C/10 mmHg (lit.)
• density: 1.106 g/mL at 25 °C (lit.)
• SMILES string: COC(=O)[C@H]1COC(C)(C)O1
• InChI: 1S/C7H12O4/c1-7(2)10-4-5(11-7)6(8)9-3/h5H,4H2,1-3H3/t5-/m1/s1
• InChI key: DOWWCCDWPKGNGX-RXMQYKEDSA-N

Description

Application

Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate may be used as a starting material to synthesize (2R)-[1-²H₂]-glycerol, a probe to study the stereochemistry of glycerol metabolism in Streptomyces cattleya. It may also be used to synthesize organic building blocks like (R)-2,3-dihydroxy-3-methylbutyl toluene-p-sulfonate and (2S,8R)-2-amino-8-[(R) 2,2-dimethyl-1,3-dioxolan-4-yl]-8-oxooctanoic acid.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 167.0 °F - closed cup
• flash_point_c: 75 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter