298980

o-Tolylmagnesium bromide solution

2.0 M in diethyl ether

• Synonym(s): 2-Methylphenylmagnesium bromide, 2-Tolylmagnesium bromide, o-Methylphenylmagnesium bromide, Bromo(2-methylphenyl)magnesium, Bromo-o-tolylmagnesium
• Linear Formula: CH₃C₆H₄MgBr
• CAS Number: 932-31-0
• Molecular Weight: 195.34
• MDL number: MFCD00010350
• UNSPSC Code: 12352103
• PubChem Substance ID: 24858005
• NACRES: NA.22

Properties

• reaction suitability: reaction type: Grignard Reaction
• concentration: 2.0 M in diethyl ether
• density: 1.013 g/mL at 25 °C
• SMILES string: Cc1ccccc1[Mg]Br
• InChI: 1S/C7H7.BrH.Mg/c1-7-5-3-2-4-6-7;;/h2-5H,1H3;1H;/q;;+1/p-1
• InChI key: DVXDIGKNJYSMFM-UHFFFAOYSA-M

Description

Application

o-Tolylmagnesium bromide solution can be used to prepare:

• An iridium(I) mesityl complex named Ir(o-tolyl)(CO)(dppe).
• 4-(2-Methylphenyl)-4-oxobutanoic acid, a key intermediate for the synthesis of M1 muscarinic selective agonist AC-42 derivatives.

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H302,H314,H336
• pcodes: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
• target_organs: Central nervous system
• supp_hazards: EUH014,EUH019
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: -40.0 °F
• flash_point_c: -40 °C