Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

View All Documentation

264466

Sigma-Aldrich

2,6-Difluorophenol

98%

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
F2C6H3OH
CAS Number:
28177-48-2
Molecular Weight:
130.09
Beilstein/REAXYS Number:
2043613
EC Number:
248-884-9
MDL number:
MFCD00002158
UNSPSC Code:
12352100
PubChem Substance ID:
24856018
NACRES:
NA.22

Quality Level

100

assay

98%

form

solid

storage condition

protect from light

bp

59-61 °C/17 mmHg (lit.)

mp

38-41 °C (lit.)

solubility

ethanol: soluble 50 mg/mL, clear, colorless to light yellow

functional group

fluoro

storage temp.

2-8°C

SMILES string

Oc1c(F)cccc1F

InChI

1S/C6H4F2O/c7-4-2-1-3-5(8)6(4)9/h1-3,9H

InChI key

CKKOVFGIBXCEIJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

2,6-difluorophenol undergoes oxidative polymerization in the presence of the Fe-N,N′-bis(salicylidene)ethylenediamine (salen) complex (catalyst) and hydrogen peroxide (oxidizing agent) to give poly(2,6-difluoro-1,4-phenylene oxide).

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Sol. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

wgk_germany

WGK 3

flash_point_f

136.4 °F - closed cup

flash_point_c

58 °C - closed cup

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKBW3077V
MKBH6851V
63296TJ
07815PH
07001KE

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J Qiu et al.
Journal of medicinal chemistry, 42(2), 329-332 (1999-02-02)
3-(Aminomethyl)-2,6-difluorophenol (6) and 4-(aminomethyl)-2, 6-difluorophenol (7) were synthesized in eight and four steps, respectively, starting from 2,6-difluorophenol, to test the potential of the 2,6-difluorophenol moiety to act as a lipophilic bioisostere of a carboxylic acid. Compounds 6 and 7 are
Oxidative Polymerization of 2,6-Difluorophenol to Crystalline Poly(2,6-difluoro-1,4-phenylene oxide).
Ikeda R, et al.
Macromolecules, 33(18), 6648-6652 (2000)
Jiasong Li et al.
Biochemistry, 58(17), 2218-2227 (2019-04-05)
Cysteine dioxygenase (CDO) is a nonheme iron enzyme that adds two oxygen atoms from dioxygen to the sulfur atom of l-cysteine. Adjacent to the iron site of mammalian CDO, there is a post-translationally generated Cys-Tyr cofactor, whose presence substantially enhances
Akira Ohashi et al.
Talanta, 146, 789-794 (2015-12-24)
The solubilities of several cobalt(III) chelates (CoL3) with in supercritical carbon dioxide (SC-CO2) were investigated in the presence of fluorine- and trifluoromethyl-substituted phenols (PhOH) using UV-vis spectrophotometry. Solubility enhancement of CoL3 complexes in SC-CO2 was accomplished by adding PhOH. The

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service