254819
Hydroquinidine hydrochloride
98%
Synonym(s):
Dihydroquinidine hydrochloride
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About This Item
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Quality Level
assay
98%
form
powder
optical activity
[α]20/D +185.2°, c = 1.3 in H2O
mp
277-279 °C (lit.)
functional group
hydroxyl
SMILES string
Cl.CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c3ccnc4ccc(OC)cc34
InChI
1S/C20H26N2O2.ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3;1H/t13-,14-,19+,20-;/m0./s1
InChI key
MULXTQKDWYBJMO-VJAUXQICSA-N
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Journal of mass spectrometry : JMS, 45(6), 635-642 (2010-06-09)
Atmospheric pressure (AP) matrix-assisted laser desorption/ionization (MALDI) is known to suffer from poor ion transfer efficiencies as compared to conventional vacuum MALDI (vMALDI). To mitigate these issues, a new AP-MALDI ion source utilizing a coaxial gas flow was developed. Nitrogen
Nederlands tijdschrift voor geneeskunde, 147(13), 585-587 (2003-04-19)
Two women, aged 77 and 73 years, and one man, aged 71 years, were admitted because of a serious adverse drug reaction (ADR). The first woman had a probable adverse drug reaction caused by digoxin after the addition of a
Short QT syndrome in infancy. Therapeutic drug monitoring of hydroquinidine in a newborn infant.
British journal of clinical pharmacology, 72(6), 982-984 (2011-06-29)
The Journal of organic chemistry, 77(16), 7076-7080 (2012-07-28)
A first approach for catalytic asymmetric Strecker reaction of aldehydes with a secondary amine in the presence of sodium fluoride using hydroquinine as chiral catalyst was developed. The catalytic system gave α-aminonitriles in excellent yields (up to 95%) and high
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 21(2), 81-86 (2000-08-11)
An abnormal neuronal excitability in myotonic dystrophy (MD) might contribute to psychomotor and behavioral disturbances of MD patients. To gain new insights into the pathophysiology of MD, we determined whether the antiarrhythmic drug hydroquinidine could ameliorate apathy and hypersomnia besides
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