Skip to Content
MilliporeSigma
All Photos(3)

Documents

159530

Sigma-Aldrich

2-Bromo-4′-methylacetophenone

90%

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
CH3C6H4COCH2Br
CAS Number:
619-41-0
Molecular Weight:
213.07
EC Number:
210-595-0
MDL number:
MFCD00000203
UNSPSC Code:
12352100
PubChem Substance ID:
24849819
NACRES:
NA.22

assay

90%

bp

105 °C/0.1 mmHg (lit.)

mp

45-49 °C (lit.)

storage temp.

2-8°C

SMILES string

Cc1ccc(cc1)C(=O)CBr

InChI

1S/C9H9BrO/c1-7-2-4-8(5-3-7)9(11)6-10/h2-5H,6H2,1H3

InChI key

KRVGXFREOJHJAX-UHFFFAOYSA-N

General description

2-Bromo-4′-methylacetophenone is an α-bromoketone.

Application

2-Bromo-4′-methylacetophenone was used in the general fluorous thiol quenching method. It was also used in the preparation of hydroxyquinolinone and N-derivatized carboxamides.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Miroslav Soural et al.
Journal of combinatorial chemistry, 9(5), 793-796 (2007-08-07)
A highly efficient solid-phase synthesis of 2-substituted-3-hydroxy-4(1H)-quinolinone-7-carboxamides was developed using anthranilates and bromoketones as the key synthons. Primary amines immobilized to an acid-cleavable BAL linker were acylated with 1-methyl-2-aminoterephtalate. After cleavage of the methyl ester, bromoketones were used to form
Use of fluorous silica gel to separate fluorous thiol quenching derivatives in solution-phase parallel synthesis
Zhang W, et al.
Tetrahedron, 58(20), 3871-3875 (2002)
Hana Elshaflu et al.
Frontiers in chemistry, 6, 247-247 (2018-07-19)
The novel approach in the treatment of complex multifactorial diseases, such as neurodegenerative disorders and cancer, requires a development of efficient multi-targeting oriented drugs. Since oxidative stress significantly contributes to the pathogenesis of cancer and neurodegenerative disorders, potential drug candidates

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service