105120
2-Bromo-2′-acetonaphthone
99%
Synonym(s):
Bromomethyl 2-naphthyl ketone
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About This Item
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assay
99%
mp
82-84 °C (lit.)
solubility
acetonitrile: soluble
functional group
bromo
SMILES string
BrCC(=O)c1ccc2ccccc2c1
InChI
1S/C12H9BrO/c13-8-12(14)11-6-5-9-3-1-2-4-10(9)7-11/h1-7H,8H2
InChI key
YHXHHGDUANVQHE-UHFFFAOYSA-N
Gene Information
human ... PTPN6(5777)
General description
2-Bromo-2′-acetonaphthone is used for derivatization of captopril to develop a fast and sensitive high-performance liquid chromatographic method for the determination of captopril in plasma.2-Bromo-2′-acetonaphthone converts tetra-acids extracted from calcium naphthenate deposits to 2-naphthacyl derivatives.
Application
2-Bromo-2′-acetonaphthone was used to determine the concentration of tetra-acids in calcium naphthenate deposits. 2-Bromo-2′-acetonaphthone was used as derivation reagent for determination of fatty acids extracted from Botryococcus braunii by HPLC.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
Storage Class
8A - Combustible corrosive hazardous materials
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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International journal of pharmaceutics, 276(1-2), 163-173 (2004-04-29)
To improve the drug absorption into and across the skin, fatty acids extracted from Botryococcus braunii were evaluated using in vitro and in vivo techniques with Wistar rats as the animal model. Palmitic acid (C16:0), oleic acid (C18:1), linoleic acid
Journal of chromatography. A, 1200(2), 136-143 (2008-06-17)
A method is described which allows to determine the content of the so-called C(80) tetra-acid molecules (TA) in calcium naphthenate deposits. The method consists of four steps. Molecules present in the deposit are dissolved in a mixture of toluene and
Pharmaceutica acta Helvetiae, 73(6), 303-306 (1999-08-12)
A rapid, simple and sensitive high-performance liquid chromatographic method for the determination of captopril in plasma has been developed. Captopril is derivatized with a new reagent, 2-bromo-2'-acetonaphthone to form a product that showed ultraviolet-absorbing properties. For plasma samples, the protein
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