The ultimate goal of most antisense research is to develop therapeutic agents for diseases such as diabetes, cancer, and HIV/ AIDS. Phosphorothioate oligonucleotides (commonly referred to as S-oligos) are often the molecules of choice because of their resistance to cellular nuclease degradation.
Human epithelial intestinal colonic organoids can be used as an alternative to Caco-2 drug permeability assays for drug screening and compound toxicity testing.
Properties of lipid formulations can vary depending on the composition (cationic, anionic, neutral lipid species), however, the same preparation method can be used for all lipid vesicles regardless of composition. The general elements of the procedure involve preparation of the lipid for hydration, hydration with agitation, and sizing to a homogeneous distribution of vesicles.
Cancer research strives to not only identify the cause, but also methods for detection, treatment, and prevention. Learn more about our contributions to cancer research in academic and industrial settings.
Rooted in physiology and biochemistry, cell and development biology features an interdisciplinary approach to understand intracellular and extracellular dynamics.
Cell signaling refers to the stimuli-driven communication cascade between cells. Learn more about cell signaling processes and protocols to study complex cellular processes.
Immunology covers all aspects of the immune system, including physiological functioning and malfunctions, in all multicellular organisms. Learn more about our resources for immunology research including articles and protocols.