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X7375

Sigma-Aldrich

黄嘌呤

≥99%

同義詞:

2,6-二羟基嘌呤

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About This Item

經驗公式（希爾表示法）:
C5H4N4O2
CAS號碼:
69-89-6
分子量：:
152.11
Beilstein:
8733
EC號碼:
200-718-6
MDL號碼:
MFCD00078453
分類程式碼代碼:
41106305
PubChem物質ID:
24902156
NACRES:
NA.51

生物源

synthetic (organic)

品質等級

300

化驗

≥99%

形狀

powder

溶解度

1 M NaOH: soluble 50 mg/mL, clear to slightly hazy
NH4OH: freely soluble
NaOH: freely soluble

SMILES 字串

O=C1NC(=O)c2nc[nH]c2N1

InChI

1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)

InChI 密鑰

LRFVTYWOQMYALW-UHFFFAOYSA-N

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相關類別

一般說明

黄嘌呤是在鸟嘌呤脱氨酶存在的情况下由鸟嘌呤合成。黄嘌呤氧化酶催化由次黄嘌呤生成黄嘌呤并随后分解为尿酸。黄嘌呤衍生物存在于咖啡、茶和可可种子中。黄嘌呤被认为是生成药理活性化合物的先导物。

應用

黄嘌呤已用于构巢曲霉转运试验中的非放射性标记底物混合物。它还被用作黄嘌呤氧化酶的底物，用于鳃细胞和藻类细胞产生超氧阴离子。

生化／生理作用

高水平黄嘌呤与自毁容貌综合征等代谢紊乱有关。基于黄嘌呤的生物传感器可用于检测食品和临床样品中的黄嘌呤。肾衰竭、痛风和黄嘌呤尿患者的血液和尿液样本均显示高水平的黄嘌呤。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

分析證明 (COA)

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存取文件庫

Biosensing methods for xanthine determination: a review
Pundir CS and Devi R
Enzyme and Microbial Technology, 57, 55-62 (2014)
Transport Assays in Aspergillus nidulans
Krypotou E and Diallinas G
Molecular Microbiology, 3(22), 1-5 (2013)
D L Krebs et al.
Methods in cell science : an official journal of the Society for In Vitro Biology, 21(1), 57-68 (2000-03-25)
Murine B cell lines such as WEHI-231, BAL17 and M12.4.1 are frequently used as model systems to study signal transduction, cell cycle regulation, and apoptosis. Dissection of these processes often involves expressing exogenous genes in these cells. Electroporation is an
Fish gill damage by the dinoflagellate Alexandrium catenella from Chilean fjords: synergistic action of ROS and PUFA
Mardones JI, et al.
Harmful Algae, 49(22), 40-49 (2015)
Xanthine scaffold: scope and potential in drug development
Singh N, et al.
Heliyon, 4(10), e00829-e00829 (2018)
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Uric Acid in Cell Culture

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HPLC Analysis of Xanthines on Purospher® STAR RP-18 endcapped

Xanthine is a purine base found in most human body tissues and fluids as well as in other organisms. Methylated xanthines (methylxanthines), which include caffeine, paraxanthine, theobromine, and theophylline, commonly used for their effects as mild stiµlants and as bronchodilators, notably in the treatment of asthma symptoms. This application shows the efficient separation of several common xanthines and may be applied their analysis in any number of desired matrices.

HPLC Analysis of Xanthines on Purospher® STAR RP-18 endcapped

Separation of Hypoxanthine, ≥99.0%; Xanthine, ≥99%; 7-Methylxanthine, ≥98.0% (HPLC); 3-Methylxanthine; 1-Methylxanthine, ≥97.0% (HPLC); Theobromine, ≥98.0%; 1,7-Dimethylxanthine, ~98%, solid; Theophylline, anhydrous, ≥99%, powder; Specimen capsules, microporous, average pore diameter 120 μm

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