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一般說明
Formerly E.C.1.1.3.22
研究领域： 细胞循环黄嘌呤黄嘌呤氧化酶（XO）是一种同源二聚体。它由两个亚单位组成，每个亚单位由一个钼中心和两个铁硫（2Fe-2S）中心组成。
應用
利用牛乳中的黄嘌呤氧化酶进行超氧化物歧化酶活性测定。黄嘌呤氧化酶可用于生产安培生物传感器和设计抗XO类黄酮抑制剂，用于治疗炎症性疾病、痛风和高尿酸血症。由于醛氧化，它也可用于合成超氧化物。
生化／生理作用
木糖氧化酶是一种含钼酶，存在于细胞质中，能够被黄酮类化合物有效抑制。它在一些药物和嘌呤嘧啶代谢中有重要作用。它被认为是活性氧簇的生物来源。
黄嘌呤氧化酶广泛分布于多种组织中，在内皮细胞和上皮细胞中的表达量尤其高。在受感染的组织中，黄嘌呤氧化酶的表达也会增加，由于它能够产生活性氧，因此被证明具有抗微生物的作用。黄嘌呤氧化酶在催化次黄嘌呤羟基化为黄嘌呤的过程中起重要作用。之后，黄嘌呤转化为尿酸，由肾脏排出体外。
單位定義
在 pH 值为 7.5、25°C 条件下，1 个单位的黄嘌呤每分钟转化为尿酸 1.0 μmol/min。次黄嘌呤作为底物时，可获得约 50% 的活性。
外觀
含 1 mM 水杨酸钠的 2.3 M (NH4)2SO4 混悬液
分析報告
双缩脲法测定蛋白质
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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文章
Instructions for working with enzymes supplied as ammonium sulfate suspensions
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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