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About This Item
經驗公式（希爾表示法）:
C26H20N2O
CAS號碼:
分子量：:
376.45
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推薦產品
產品名稱
XE-991, ≥98% (HPLC)
化驗
≥98% (HPLC)
顏色
white to beige
溶解度
DMSO: >20 mg/mL
起源
Merck & Co., Inc., Kenilworth, NJ, U.S.
儲存溫度
2-8°C
SMILES 字串
O=C1c2ccccc2C(Cc3ccncc3)(Cc4ccncc4)c5ccccc15
InChI
1S/C26H20N2O/c29-25-21-5-1-3-7-23(21)26(17-19-9-13-27-14-10-19,18-20-11-15-28-16-12-20)24-8-4-2-6-22(24)25/h1-16H,17-18H2
InChI 密鑰
KHJFBUUFMUBONL-UHFFFAOYSA-N
應用
XE-991已被利用KCNQ（Kv7.2 / 7.3）抑制剂，以检查M电流抑制是否影响催产素受体（TGOT）介导的去极化。也曾作为 KCNQ 抑制剂用于研究河豚毒素（TTX）存在时小鼠胆碱能中间神经元（ChIs）膜电位超射/欠射的离子机制。
生化／生理作用
XE-991 是一种 KCNQ 通道阻滞剂。
XE-991 是一种 KCNQ 通道阻滞剂；它比利诺哌啶（目录号L-134）更有效。
特點和優勢
该化合物是由Merck & Co., Inc., Kenilworth, NJ, U.S.开发的。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单，请单击此处。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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