U6758

UCL 2077

≥98% (HPLC), solid

• 同義詞: (3-Triphenylmethylaminomethyl)pyridine
• 經驗公式（希爾表示法）: C₂₅H₂₂N₂
• CAS號碼: 918311-87-2
• 分子量：: 350.46
• MDL號碼: MFCD00585879
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329827644
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: solid
• 顏色: white
• 溶解度: DMSO: soluble >20 mg/mL; H₂O: insoluble
• SMILES 字串: C(NC(c1ccccc1)(c2ccccc2)c3ccccc3)c4cccnc4
• InChI: 1S/C25H22N2/c1-4-12-22(13-5-1)25(23-14-6-2-7-15-23,24-16-8-3-9-17-24)27-20-21-11-10-18-26-19-21/h1-19,27H,20H2
• InChI 密鑰: PQFNWDHABGBCHB-UHFFFAOYSA-N

描述

應用

UCL 2077 has been used for slow afterhyperpolarization (sAHP) studies in thalamic paraventricular nucleus (PVT) neurons. UCL 2077 has also been used for studying its effects on the increase in excitability of hippocampal pyramidal cells.

生化／生理作用

UCL 2077 is a slow afterhyperpolarization (sAHP) channel blocker.

準備報告

UCL 2077 is soluble in DMSO at a concentration >20 mg/ml and is insoluble in water.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H315,H319,H335
• 防範說明: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Faceshields, Gloves