SRP4304

NGF-beta from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• 同義詞: Nerve Growth Factor β, Ngf, Ngfb
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 生物源: mouse
• 重組細胞: expressed in E. coli
• 化驗: ≥98% (SDS-PAGE)
• 形狀: lyophilized
• 效力: 0.2 ng/mL ED₅₀
• 分子量: ~13.4 kDa
• 包裝: pkg of 20 μg
• 雜質: endotoxin, tested
• NCBI登錄號: P01139
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: mouse ... Ngf(18049)

描述

一般說明

Nerve growth factor-β (NGF-β) belongs to the neurotrophin family. The active form of human NGF-β is a homodimer, non-glycosylated chain.

生化／生理作用

Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. It brings pro-survival effects with the help of receptor tyrosine kinase TrkA. NGF-β is associated with diabetic neuropathy and ischemic heart disease. It is also involved in airway nerve system. NGF-β is also responsible for the pain which is linked with osteoarthritis (OA). It is involved in liver fibrosis, carcinogenesis, angiogenesis and cholangiocyte proliferation.

外觀

Lyophilized without any additives.

重構

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL containing 1% HSA or BSA. The solution can be diluted into other aqueous buffers and stored at 4°C for 2-7 days or store at –20°C for future use.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable